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RNAi-mediated Control of Aflatoxins in Peanut: Method to Analyze Mycotoxin Production and Transgene Expression in the Peanut/Aspergillus Pathosystem
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Infants exposure to aflatoxin M₁ as a novel foodborne zoonosis

Wael F El-Tras1, Nevein N El-Kady, Ahmed A Tayel

  • 1Department of Hygiene and Preventive Medicine (Zoonoses), Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. wael_tras@yahoo.com

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
|August 26, 2011
PubMed

Insights

Aflatoxin M(1) in infant formula and breast milk poses a health risk to newborns in Egypt. Maternal breast milk showed a higher risk of aflatoxin exposure than infant formula.

Area of Science:

  • Food Safety
  • Toxicology
  • Public Health

Background:

  • Aflatoxin M(1) (AFM(1)) is a significant foodborne contaminant.
  • Infant formula milk powder (IFMP) and maternal breast milk (MBM) are critical nutrition sources for newborns.
  • Investigating AFM(1) in these sources is crucial for newborn health risk assessment in Egypt.

Purpose of the Study:

  • To investigate the occurrence of AFM(1) in IFMP and MBM in Egypt.
  • To assess the associated health risks for newborns.
  • To identify potential sources and correlations of AFM(1) contamination.

Main Methods:

  • Collection and analysis of 125 IFMP and 125 MBM samples.
  • Utilized competitive ELISA for AFM(1) detection.
  • Calculated relative risk (RR) and mean concentrations of AFM(1).

Main Results:

  • AFM(1) was detected in both IFMP and MBM, with higher concentrations in MBM (74.413 ± 7.070 ng/l) vs. IFMP (9.796 ± 1.036 ng/l).
  • Relative risk of AFM(1) exposure was higher via MBM (RR=1.6) than IFMP.
  • Consumption of raw milk by mothers significantly correlated with AFM(1) in MBM.

Conclusions:

  • AFM(1) exposure is a significant risk for Egyptian newborns through both MBM and IFMP.
  • Maternal consumption of raw milk is a key factor in MBM contamination.
  • AFM(1) may be an etiological factor for a novel foodborne zoonosis, Aflatoxicosis M(1).

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