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Related Concept Videos

Structures of the Endocrine System00:59

Structures of the Endocrine System

The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
What is the Endocrine System?00:46

What is the Endocrine System?

The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
The Endocrine System01:29

The Endocrine System

The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that every...
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.

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Related Experiment Video

Updated: May 29, 2026

Ex Vivo Calcium Imaging for Visualizing Brain Responses to Endocrine Signaling in Drosophila
06:49

Ex Vivo Calcium Imaging for Visualizing Brain Responses to Endocrine Signaling in Drosophila

Published on: June 2, 2018

[Disperse endocrine system and APUD concept].

I V Mil'to, I V Sukhodolo, E A Gereng

    Morfologiia (Saint Petersburg, Russia)
    |August 27, 2011
    PubMed
    Summary

    This review explores the challenges in understanding the diffuse endocrine system and amine precursor uptake and decarboxylation (APUD) system. It highlights the crucial roles of single endocrine cells in regulating bodily functions.

    Area of Science:

    • Endocrinology
    • Cell Biology
    • Histology

    Context:

    • The diffuse endocrine system and the amine precursor uptake and decarboxylation (APUD) system represent complex networks of hormone-producing cells.
    • Understanding their morphology and cellular biology is essential for comprehending systemic regulation.
    • Debatable issues in single endocrine cell biology require comprehensive review.

    Purpose:

    • To review the historical discovery and morphological study methods of the diffuse endocrine and APUD systems.
    • To elucidate the developmental origins, structural organization, and physiological functions of endocrine cells.
    • To discuss the significance of individual endocrine cells in organismal function regulation.

    Summary:

    • This review synthesizes current knowledge on the diffuse endocrine system and the APUD system, focusing on morphology and cellular biology.

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  • It covers the historical context, methodological approaches, developmental pathways, and structural aspects of these systems.
  • The physiological roles and regulatory significance of single endocrine cells are critically examined.

    • Impact:

    • Provides a consolidated overview of the diffuse endocrine and APUD systems for researchers and clinicians.
    • Highlights areas of debate and future research directions in endocrine cell biology.
    • Underscores the importance of single endocrine cells in maintaining organismal homeostasis.