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Published on: October 2, 2020
Cognitive function among hemodialysis patients in Japan
Gen Odagiri1, Norio Sugawara, Atsuhiro Kikuchi
1Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Japan. nsuga3@yahoo.co.jp.
Annals of General Psychiatry
|August 27, 2011
Summary
Cognitive impairment affects 18.8% of hemodialysis (HD) patients, with older individuals at higher risk. Undergoing HD treatment is an independent risk factor for cognitive decline, necessitating clinical monitoring.
Area of Science:
- Nephrology
- Geriatrics
- Neuroscience
Background:
- Over 290,000 patients in Japan undergo hemodialysis (HD).
- Cognitive impairment prevalence increases with age and is common in elderly HD patients.
- Assessing cognitive function in HD patients is crucial due to potential health implications.
Purpose of the Study:
- To evaluate the prevalence of cognitive impairment in hemodialysis patients.
- To investigate the relationship between cognitive impairment and clinical characteristics in HD patients.
- To identify hemodialysis as a potential risk factor for cognitive decline.
Main Methods:
- Cross-sectional study design.
- Administered the Mini-Mental State Examination (MMSE) to 154 HD outpatients.
- Compared HD patients with 852 participants from the general population (Iwaki Health Promotion Project 2010).
Main Results:
- 18.8% of HD patients exhibited cognitive impairment.
- Cognitive impairment was more prevalent in HD patients aged 50 and older.
- Hemodialysis was a significant independent factor associated with lower MMSE scores (OR = 2.28).
- Higher education levels correlated with better MMSE scores among HD patients.
Conclusions:
- Cognitive impairment is highly prevalent in HD patients, impacting hospitalization and life expectancy.
- Hemodialysis treatment is an independent risk factor for cognitive impairment.
- Clinicians must actively monitor and manage cognitive impairment in HD patients.
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