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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 29, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

Deep brain stimulation emerging indications.

Travis S Tierney1, Tejas Sankar, Andres M Lozano

  • 1Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada.

Progress in Brain Research
|August 27, 2011
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) shows promise for Parkinson's disease, depression, and Alzheimer's disease by modulating brain circuits. Further research will expand its therapeutic applications.

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Related Experiment Videos

Last Updated: May 29, 2026

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09:46

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Published on: March 8, 2015

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Area of Science:

  • Neurology
  • Neurosurgery
  • Psychiatry

Background:

  • Deep brain stimulation (DBS) is an evolving surgical treatment.
  • Modulating neural circuits offers therapeutic potential for various neurological and psychiatric conditions.

Purpose of the Study:

  • To review the rationale, safety, and efficacy of DBS for Parkinson's disease, treatment-resistant depression, and Alzheimer's type dementia.
  • To explore disease mechanisms and supporting data for DBS therapeutic value.

Main Methods:

  • Review of existing literature on DBS for specific neurological and psychiatric conditions.
  • Analysis of disease mechanisms and clinical data to assess therapeutic value.

Main Results:

  • DBS demonstrates beneficial effects in patients with Parkinson's disease, treatment-resistant depression, and potentially Alzheimer's disease.
  • Evidence supports the modulation of motor, mood, and cognitive circuits through DBS.

Conclusions:

  • DBS is a promising intervention for multiple conditions, with expanding applications.
  • Continued research on safety and efficacy will drive the future use of DBS in clinical practice.