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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

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Updated: May 29, 2026

Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
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Published on: September 26, 2016

Raman's "effect" on molecular imaging.

Cristina L Zavaleta1, Moritz F Kircher, Sanjiv S Gambhir

  • 1Molecular Imaging Program at Stanford, Department of Radiology and Bio-X Program, Stanford, California, USA.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|August 27, 2011
PubMed
Summary
This summary is machine-generated.

Raman spectroscopy, a sensitive optical imaging technique, is advancing from chemical analysis to studying molecular interactions in cells and animals. It is now being developed for clinical diagnostics using endoscopy.

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Area of Science:

  • Biophotonics
  • Molecular Imaging
  • Optical Spectroscopy

Background:

  • Raman spectroscopy is a highly sensitive optical technique.
  • Traditionally used for chemical analysis, its application has expanded.
  • It offers multiplexing capabilities for detailed molecular insights.

Purpose of the Study:

  • To highlight the evolution of Raman spectroscopy in molecular imaging.
  • To showcase its application in biological systems and preclinical models.
  • To discuss its translation into clinical diagnostic tools.

Main Methods:

  • Harnessing the sensitivity and multiplexing features of Raman spectroscopy.
  • Applying the technique for imaging and spectral analysis of molecular interactions.
  • Utilizing endoscopic strategies for clinical translation.

Main Results:

  • Demonstrated successful application in cell populations.
  • Validated utility in preclinical animal models.
  • Initiated translation into clinical diagnostic settings.

Conclusions:

  • Raman spectroscopy is a versatile tool for molecular imaging.
  • Its capabilities extend from basic research to clinical applications.
  • Endoscopic Raman spectroscopy shows promise for novel diagnostics.