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Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling
Chenxuan Wang1, Xiaobo Mao, Aihua Yang
1National Center for Nanoscience and Technology, Beijing 100190, China.
Abstract:
The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO(3)Na)(4)) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.
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