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Updated: May 29, 2026

08:59
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
Published on: September 27, 2019
Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold
Masayuki Endo1, Yangyang Yang, Tomoko Emura
1Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida-ushinomiyacho, Kyoto 606-8501, Japan. endo@kuchem.kyoto-u.ac.jp
Abstract:
A novel DNA scaffold, called a DNA slit, was designed for the programmed positioning of Au nanoparticles (AuNPs), and various patterns of thiolated DNA slits were constructed. AuNPs were correctly placed at the predesigned positions in the thiolated DNA slits, indicating that the thiolated staples and the slit cavities guide the correct assembly of AuNPs.

