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Related Concept Videos

Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

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Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
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Ongoing measles outbreak in Romania, 2011.

A Stanescu1, D Janta, E Lupulescu

  • 1National Institute of Public Health, National Centre for Communicable Diseases Surveillance and Control, Bucharest, Romania. aurora.stanescu@insp.gov.ro

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|August 30, 2011
PubMed
Summary
This summary is machine-generated.

Romania has faced a significant measles outbreak since 2011, primarily affecting unvaccinated young children. Urgent vaccination strategies are needed to control the spread and prevent future measles epidemics.

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Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • Romania has experienced a widespread measles outbreak since January 2011.
  • The outbreak has affected 29 out of 42 districts, with over 2,072 cases reported.

Purpose of the Study:

  • To report on the scale and demographics of the ongoing measles outbreak in Romania.
  • To highlight the critical need for increased vaccination coverage.

Main Methods:

  • Analysis of notified measles cases across Romanian districts.
  • Demographic breakdown of cases, focusing on age groups and vaccination status.

Main Results:

  • A total of 2,072 measles cases were notified.
  • The majority of cases occurred in unvaccinated children, particularly those aged one to four years (893 cases).
  • The north-western region of Romania reported the highest number of cases.

Conclusions:

  • The measles outbreak underscores the vulnerability of unvaccinated populations.
  • There is an urgent need for targeted interventions to improve measles-mumps-rubella (MMR) vaccine uptake.
  • Achieving high vaccination coverage with two doses of MMR is essential for controlling the outbreak.