Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pathophysiology of preeclampsia.

L C Gilstrap1, N F Gant

  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.

Seminars in Perinatology
|April 1, 1990
PubMed
Summary

Preeclampsia and pregnancy-induced hypertension involve vasospasm, a condition where blood vessels narrow. This vasospasm causes widespread organ system dysfunction in affected women.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In vitro quantification of dexamethasone-induced surfactant protein B expression in human lung cells.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2004
Same author

Antenatal corticosteroids in women with preterm premature rupture of the membranes.

Clinics in perinatology·2002
Same author

Clinical experience reported by candidates for the American Board of Obstetrics and Gynecology 1995 and 1997 oral examinations.

American journal of obstetrics and gynecology·2001
Same author

Urinary tract infections during pregnancy.

Obstetrics and gynecology clinics of North America·2001
Same author

Effects of pregnancy on specific diseases.

Seminars in perinatology·2001
Same author

Other factors/conditions associated with cerebral palsy.

Seminars in perinatology·2000

Area of Science:

  • Obstetrics and Gynecology
  • Cardiovascular Physiology

Background:

  • Preeclampsia and pregnancy-induced hypertension are significant maternal health concerns.
  • Understanding the underlying pathophysiology is crucial for effective management.

Purpose of the Study:

  • To identify the primary pathophysiologic event in preeclampsia and pregnancy-induced hypertension.
  • To elucidate the consequences of this event on maternal organ systems.

Main Methods:

  • Review of existing literature on hypertensive disorders of pregnancy.
  • Analysis of pathophysiologic mechanisms and clinical manifestations.

Main Results:

  • Vasospasm is identified as the central pathophysiologic event.
  • Vasospasm leads to multi-organ system dysfunction.

Conclusions:

  • Vasospasm is the key mechanism driving the pathology in preeclampsia and pregnancy-induced hypertension.
  • The widespread organ dysfunction stems from this vascular abnormality.

Related Experiment Videos