Insights into membrane insertion based on studies of colicins
Related Experiment Videos
M W Parker1, A D Tucker, D Tsernoglou
1European Molecular Biology Laboratory, Heidelberg, FRG.
Trends in Biochemical Sciences
|April 1, 1990
Abstract:
The recently determined three-dimensional structure of the pore-forming domain of colicin A has led to a hypothetical model for membrane insertion and channel formation. Certain features of this model have implications for understanding the mechanism of membrane insertion by other toxins and may have a broader relevance to protein transport in general.