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Updated: May 29, 2026

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
Applications of hyperpolarized agents in solutions
Jan Henrik Ardenkjaer-Larsen1, Haukur Jóhannesson, J Stefan Petersson
1GE Healthcare, 1808 Frederiksberg C, Denmark. jan.henrik.ardenkjaer-larsen@ge.com
This review covers pulse sequences for hyperpolarized magnetic resonance imaging (MRI). It explores vascular and metabolic applications of hyperpolarized agents, highlighting their rapid development in various medical fields.
Area of Science:
- Medical Imaging
- Biophysics
Background:
- Hyperpolarized magnetic resonance imaging (MRI) offers enhanced signal-to-noise ratios.
- Hyperpolarized agents enable real-time monitoring of physiological processes.
Purpose of the Study:
- To provide an overview of pulse sequences tailored for hyperpolarized MRI.
- To review current and emerging applications of hyperpolarized agents in aqueous solutions.
Main Methods:
- Review of existing literature on hyperpolarized MRI techniques.
- Compilation of applications across vascular and metabolic imaging.
Main Results:
- Detailed discussion of vascular applications including angiography, perfusion, and catheter tracking.
- Exploration of metabolic applications in oncology, cardiology, neurology, and pH mapping.
Conclusions:
- Hyperpolarized MRI is a rapidly evolving field with expanding clinical potential.
- The review format is necessary due to the fast pace of new application development.
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