Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investing in scholarship for health professions education: Learning from the past to move into the future.

Medical teacher·2021
Same author

MDRO Beijing Consensus Meeting Report: Global burden of multidrug-resistant organisms' current antimicrobial resistance problems in Asia-Pacific.

Journal of global antimicrobial resistance·2016
Same author

The educational environment and self-perceived clinical competence of senior medical students in a Malaysian medical school.

Education for health (Abingdon, England)·2009
Same author

Occupational infections.

The Malaysian journal of pathology·2009
Same author

Infectious diarrhoea.

The Medical journal of Malaysia·2008
Same author

In-vitro activity of quinupristin/dalfopristin, levofloxacin and moxifloxacin against fusidic acid and rifampicin-resistant strains of methicillin-resistant Staphylococcus aureus (MRSA) from Malaysian hospitals.

The Medical journal of Malaysia·2006

Related Experiment Video

Updated: May 29, 2026

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples
06:05

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples

Published on: June 14, 2024

Leptospirosis: a re-emerging infection.

V K E Lim1

  • 1Division of Pathology, Faculty of Medicine and Health, International Medical University, Kuala Lumpur, Malaysia.

The Malaysian Journal of Pathology
|August 31, 2011
PubMed
Summary
This summary is machine-generated.

Leptospirosis, a re-emerging zoonotic disease, presents diagnostic challenges due to non-specific symptoms and inadequate lab tests. Effective control relies on hygiene and rodent control, with no human vaccine currently available.

More Related Videos

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
10:47

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Published on: July 1, 2011

High-throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants During Golden Syrian Hamster Infection
11:50

High-throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants During Golden Syrian Hamster Infection

Published on: December 18, 2017

Related Experiment Videos

Last Updated: May 29, 2026

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples
06:05

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples

Published on: June 14, 2024

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
10:47

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins

Published on: July 1, 2011

High-throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants During Golden Syrian Hamster Infection
11:50

High-throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants During Golden Syrian Hamster Infection

Published on: December 18, 2017

Area of Science:

  • Infectious Diseases
  • Zoonotic Infections
  • Public Health

Background:

  • Leptospirosis is a re-emerging zoonotic infection with increasing incidence globally.
  • Outbreaks are common in developing countries, particularly in urban slums and after floods.
  • International travel and outdoor recreation increase exposure risk for individuals from developed nations.

Purpose of the Study:

  • To highlight the diagnostic challenges of leptospirosis.
  • To discuss the increasing prevalence of severe pulmonary hemorrhagic leptospirosis.
  • To emphasize current control strategies and the need for further research.

Main Methods:

  • This study is a review of the current understanding of leptospirosis.
  • It synthesizes information on epidemiology, diagnosis, clinical presentation, and control.

Main Results:

  • Leptospirosis often presents as a non-specific febrile illness, complicating early diagnosis.
  • Current rapid diagnostic tests lack sufficient sensitivity in early disease stages.
  • Severe pulmonary hemorrhagic leptospirosis is an emerging concern in various regions, including Malaysia.

Conclusions:

  • Leptospirosis diagnosis remains a significant challenge due to non-specific symptoms and limited laboratory diagnostic capabilities.
  • Control strategies primarily focus on public hygiene and rodent control.
  • There is a critical need for further research to improve understanding, diagnosis, and prevention, including the development of an effective human vaccine.