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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
The Dowager's hump: an early start?
1Institute of Gerontology, King's College London, London, UK. robert.weale@kcl.ac.uk
Background:
A recent study has shown that biomarkers relating to the variation of muscle strength with age exhibited gender differences.
Objective:
To discover whether gender differences in kyphosis and its progression with age might be explained in a related manner.
Methods:
Relevant aspects of muscular ageing, and related changes in the Cobb angle (a measure of kyphosis) were examined and linked to data on the gerontology of musculature. A hypothesis regarding embryonic antecedents was advanced.
Results:
Kyphosis appears to rest on a multifactorial basis, with age and muscular changes playing potentially important roles.
Conclusions:
The role of muscle strength as a cause of kyphosis merits further investigation. Both muscular and kyphotic studies should be repeated on the same subjects, and relevant embryonic antecedents be examined. A study of the relation between gonadal and antenatal muscular development might yield conclusive results.
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