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Updated: May 29, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Pemphigoid gestationis: a case report and review of the literature
Shannon M Campbell1, Kathryn Balazs, Michael Conroy
1Ohio University College of Osteopathic Medicine, O'Bleness Memorial Hospital Dermatology Residency Program, Athens, USA. shannoncampbell25@gmail.com
Abstract:
Pemphigoid gestationis (PG) is an uncommon autoimmune bullous disease that almost exclusively presents during pregnancy. Patients typically present with a diffuse blistering and intensely pruritic eruption that begins periumbilically and spreads to involve the rest of the body. Direct immunofluorescence demonstrating C3 in a linear pattern along the dermoepidermal junction confirms the diagnosis of PG. Corticosteroids remain the choice of therapy and early intervention is essential because of possible adverse effects of PG on the fetus. We report a case of PG and review the literature.
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