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Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Allergic Reactions02:06

Allergic Reactions

Overview
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...

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Related Experiment Video

Updated: May 29, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Infant nutrition and allergy.

Zrinjka Mišak1

  • 1Referral Centre for Paediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Klaiceva 16, 10 000 Zagreb, Croatia. zrinjka.misak@gmail.com

The Proceedings of the Nutrition Society
|September 2, 2011
PubMed
Summary

Early infant nutrition significantly impacts the risk of developing atopic diseases like asthma and eczema. Dietary modifications, including breastfeeding and timing of solid food introduction, play a crucial role in allergy prevention.

Area of Science:

  • Allergy and immunology
  • Pediatric nutrition
  • Environmental health

Background:

  • Rising incidence of atopic diseases (asthma, atopic dermatitis, food allergies) globally.
  • Genetic predisposition exists, but environmental factors, especially early nutrition, are key influences.
  • Dietary interventions are explored to mitigate allergy development.

Purpose of the Study:

  • To review the role of early infant nutrition in the development of atopic diseases.
  • To evaluate the impact of breastfeeding and complementary feeding on allergy risk.
  • To assess the effectiveness of dietary modifications for atopy prevention.

Main Methods:

  • Literature review of studies on infant feeding practices and atopic disease outcomes.
  • Analysis of data concerning breastfeeding duration and introduction of solids.

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Basophil Activation Test for Allergy Diagnosis
07:22

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Related Experiment Videos

Last Updated: May 29, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

  • Examination of evidence for specific dietary components and allergenic foods.
  • Main Results:

    • Breastfeeding shows a protective effect against atopic dermatitis and wheezing.
    • Introducing solids before 4 months may increase atopic dermatitis risk.
    • No strong evidence supports delaying solids after 6 months for allergy prevention.

    Conclusions:

    • Early nutrition is critical for long-term health and atopy prevention.
    • Breastfeeding and appropriate timing of complementary feeding are important strategies.
    • Further research into specific dietary components for active atopy prevention is warranted.