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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Analysis of cardiovascular disease in Chinese inpatients with chronic kidney disease

Xiao-Nong Chen1, Xiao-Xia Pan, Hai-Jin Yu

  • 1Department of Nephrology, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, PR China.

Internal Medicine (Tokyo, Japan)
|September 2, 2011
PubMed

Insights

Cardiovascular disease (CVD) prevalence increases with chronic kidney disease (CKD) progression, starting even in stage 1. Early screening and prevention of CVD in CKD patients are crucial.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a significant concern in patients with chronic kidney disease (CKD).
  • Understanding the prevalence of CVD across different stages of CKD is essential for effective patient management.

Purpose of the Study:

  • To determine the prevalence of cardiovascular disease (CVD) in a Chinese patient cohort across all stages of chronic kidney disease (CKD).

Main Methods:

  • Retrospective review of medical histories and laboratory results for 602 CKD patients hospitalized between January 2004 and January 2006.
  • Analysis of CVD prevalence, including coronary artery disease (CAD), left ventricular hypertrophy (LVH), and congestive heart failure (CHF), stratified by CKD stage (1-5) and dialysis status.

Main Results:

  • CVD prevalence significantly increased with CKD stage, ranging from 1.28% in stage 1 to 56.2% in stage 5 (78.51% in dialysis patients).
  • Specific CVD manifestations like CAD, LVH, and CHF also showed a progressive increase with CKD severity.
  • Over a third of patients (34.52%) presented with two or more co-morbidities related to CVD.

Conclusions:

  • Cardiovascular disease is present from the earliest stages of CKD and its incidence escalates as kidney function declines.
  • Proactive screening and preventative strategies for CVD should be implemented starting at CKD stage 1.
Abstract

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