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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Published on: January 9, 2015

[The neurotic disorders].

Shuji Honjo1, Kenji Nomura, Kikuko Kuriyama

  • 1Nagoya University, Center for Developmental Clinical Psychology and Psychiatry.

Seishin Shinkeigaku Zasshi = Psychiatria Et Neurologia Japonica
|September 3, 2011
PubMed
Summary
This summary is machine-generated.

Obsessive-compulsive disorder (OCD) in children shares a persistent 4-factor structure with adult OCD. Early-onset OCD may link to parental traits and hoarding symptoms indicate poorer long-term outcomes.

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Area of Science:

  • Child and adolescent psychiatry
  • Neuroscience
  • Developmental psychology

Context:

  • Child and adolescent psychiatry often involves managing disorders that persist into adulthood.
  • Obsessive-compulsive disorder (OCD) can manifest as early as age 3, with increasing prevalence around age 10.
  • Anorexia nervosa also shows increased incidence from approximately age 11.

Purpose:

  • To examine the association between childhood/adolescent disorders and adult disorders, focusing on obsessive-compulsive disorder (OCD).
  • To review characteristics of early-onset OCD (under age 7) and compare child/adolescent OCD with adult presentations.

Summary:

  • Early-onset OCD cases (under 7) frequently involve separation anxiety, with potential links to parental obsessional tendencies.
  • Child and adolescent OCD exhibits a stable 4-factor structure (symmetry, forbidden thoughts, cleaning, hoarding) that endures into adulthood.
  • Hoarding as a primary symptom is associated with poorer long-term prognosis in children.
  • While generally favorable, the prognosis of childhood OCD requires caution due to a potential transition to schizophrenia in some cases.

Impact:

  • Understanding the enduring nature of OCD symptom dimensions across the lifespan.
  • Identifying early indicators and risk factors for childhood-onset OCD.
  • Informing differential diagnosis and long-term management strategies for pediatric OCD.
  • Highlighting the importance of considering comorbid conditions like tics and their impact on prognosis.