[Immunomorphological changes in lichen ruber planus of the oral mucosa]

Immunomorphologic examinations of 23 biopsy specimens of the buccal mucosa of patients with lichen ruber planus have revealed changes that confirm the hypothesis on the autoimmune nature of this disease. The basic cause of clinical manifestation of lichen planus is disordered microcirculatory system of the buccal mucosa, resultant from deposition of the immune complexes and fibrin in the vessel walls and lumen.