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Updated: May 29, 2026

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
Published on: June 17, 2012
Systematic prediction of gene function in Arabidopsis thaliana using a probabilistic functional gene network
Sohyun Hwang1, Seung Y Rhee, Edward M Marcotte
1Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Abstract:
AraNet is a functional gene network for the reference plant Arabidopsis and has been constructed in order to identify new genes associated with plant traits. It is highly predictive for diverse biological pathways and can be used to prioritize genes for functional screens. Moreover, AraNet provides a web-based tool with which plant biologists can efficiently discover novel functions of Arabidopsis genes (http://www.functionalnet.org/aranet/). This protocol explains how to conduct network-based prediction of gene functions using AraNet and how to interpret the prediction results. Functional discovery in plant biology is facilitated by combining candidate prioritization by AraNet with focused experimental tests.
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