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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Microbial Interactions: Cooperation01:26

Microbial Interactions: Cooperation

Microbial cooperation involves beneficial interactions in which different species work together for individual or mutual advantage. These interactions can profoundly influence ecological dynamics and evolutionary processes, and they are essential to many pathogenic and symbiotic relationships.Nematode–Bacteria CooperationA striking example is the relationship between the Gram-negative bacterium Xenorhabdus nematophila and the parasitic nematode Steinernema carpocapsae. Juvenile nematodes...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...

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Related Experiment Video

Updated: May 29, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Neonatal Norwegian scabies: three cooperating causes.

Giulio Gualdi1, Laura Bigi, Giovanna Galdo

  • 1Department of Dermatology, University of Modena and Reggio Emilia, Italy.

Journal of Dermatological Case Reports
|September 3, 2011
PubMed
Summary

Crusted scabies is rare in infants, but this case highlights how atopic dermatitis and immune suppression can lead to unusual presentations. Consider scabies if eczema treatments fail.

Keywords:
Sarcoptes scabieiatopic dermatitisglucocorticoidsscabiestopical

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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
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Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

Area of Science:

  • Dermatology
  • Pediatrics
  • Infectious Diseases

Background:

  • Norwegian (crusted) scabies is rarely reported in infants, typically occurring in immunocompromised individuals.
  • Atopic dermatitis is a common inflammatory skin condition in infants.
  • Iatrogenic immunosuppression can increase susceptibility to infections.

Observation:

  • A case of an infant with atopic dermatitis presented with severe skin conditions.
  • Initial treatment with topical and systemic steroids for atopic dermatitis was ineffective.
  • Clinical examination and microscopic analysis of skin scrapings confirmed crusted scabies.

Findings:

  • The infant's physiological inability to scratch, atopic dermatitis, and iatrogenic immunosuppression likely contributed to the crusted scabies diagnosis.
  • This presentation of crusted scabies in an infant is highly unusual.

Implications:

  • This case suggests that crusted scabies should be considered in infants with atopic dermatitis who fail to respond to standard eczema treatments.
  • Early diagnosis and appropriate treatment are crucial for managing crusted scabies in infants.
  • Healthcare providers should be aware of the atypical presentations of scabies in vulnerable pediatric populations.