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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

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Related Experiment Video

Updated: May 29, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Multiple eruptive clear cell acanthoma.

Paola Monari1, Camillo Farisoglio, Giulio Gualdi

  • 1Department of Dermatology, University of Brescia, Brescia, Italy.

Journal of Dermatological Case Reports
|September 3, 2011
PubMed
Summary
This summary is machine-generated.

Multiple clear cell acanthomas, a rare skin condition, were successfully treated with cryotherapy. This liquid nitrogen treatment offers an effective alternative for managing multiple clear cell acanthoma cases.

Keywords:
clear cell acanthomacryotherapymultipletumor

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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A Rat Model of Compound Acne
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A Rat Model of Compound Acne

Published on: November 1, 2024

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Clear cell acanthoma is a rare benign epidermal tumor.
  • Typically presents as a solitary lesion, multiple occurrences are infrequent.
  • Unknown etiology and affects middle-aged individuals without sex predilection.

Observation:

  • A case of a 74-year-old male with multiple clear cell acanthomas on lower extremities is presented.
  • The patient was otherwise healthy.
  • Successful treatment with cryotherapy was achieved.

Findings:

  • Cryotherapy using liquid nitrogen proved effective for multiple clear cell acanthomas.
  • This case highlights an unusual presentation of multiple lesions.
  • Successful treatment outcomes were observed.

Implications:

  • Cryotherapy is a viable treatment option for multiple clear cell acanthomas.
  • Further research into the etiology of multiple clear cell acanthoma may be warranted.
  • This case contributes to the limited literature on managing multiple clear cell acanthoma.