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Related Experiment Video

Updated: May 29, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Atypical "allergic crease".

Yuval Ramot¹, Alex Maly, Abraham Zlotogorski

¹Department of Dermatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Journal of Dermatological Case Reports

|September 3, 2011

Summary

This summary is machine-generated.

Cornified papules, a new skin finding, were observed along the allergic crease in a patient with allergic rhinitis. This highlights the need for greater awareness of skin manifestations associated with this common condition.

Keywords:

allergic crease allergic rhinitis dermoscopy pediatric dermatology seborrheic keratosis like hyperplasia

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Area of Science:

Dermatology
Allergology

Background:

The allergic crease, a transverse line on the nose, is frequently seen in individuals with allergic rhinitis.
Skin manifestations associated with allergic rhinitis are infrequently documented in medical literature.

Observation:

An 18-year-old male patient with a history of allergic rhinitis presented with new-onset cornified papules.
These papules were located along the characteristic allergic crease on his nose.

Findings:

Dermoscopic evaluation showed the papules to be oval, slightly elevated, gray, and well-defined.
Histopathological analysis indicated hyperplasia resembling seborrheic keratosis, with the presence of horn cysts.

Implications:

This case reports the novel occurrence of cornified papules along the allergic crease.
Increased clinical awareness of cutaneous findings in allergic rhinitis is crucial, given its prevalence in children.