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Geographic tongue treated with topical tacrolimus
Masaya Ishibashi1, Genichi Tojo, Masahiko Watanabe
1Department of Dermatology, Tohoku University Hospital, Sendai, Japan.
Journal of Dermatological Case Reports
|September 3, 2011
Summary
Topical tacrolimus ointment effectively treated painful geographic tongue (benign migratory glossitis) in two adults. Further clinical trials are recommended to confirm this treatment
Area of Science:
- Dermatology
- Oral Medicine
- Inflammatory Disorders
Background:
- Geographic tongue, also known as benign migratory glossitis, is an inflammatory tongue condition of unknown cause.
- Characterized by migratory erythematous lesions on the tongue due to filiform papillae loss.
- Current symptomatic treatments lack rigorous evaluation.
Observation:
- Presents two adult cases of persistent and painful geographic tongue.
- Successful treatment achieved through topical application of 0.1% tacrolimus ointment.
Findings:
- This report is the first to document successful topical tacrolimus treatment for symptomatic geographic tongue.
- Topical 0.1% tacrolimus demonstrated efficacy in resolving painful lesions.
Implications:
- Topical tacrolimus shows promise as a novel treatment for symptomatic geographic tongue.
- Further clinical trials are essential to validate the efficacy and safety of topical tacrolimus.
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