Related Experiment Video

Updated: May 29, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
03:13

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Published on: June 28, 2024

Meningiomas in children: A study of 18 cases

Nirav Mehta1, Sanat Bhagwati, Geeta Parulekar

  • 1Department of Neurosurgery, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.

Journal of Pediatric Neurosciences
|September 3, 2011
PubMed
Abstract

Insights

Pediatric intracranial meningiomas are rare but can be aggressive. Complete surgical removal and benign histology lead to a good prognosis for children with these brain tumors.

Area of Science:

  • Pediatric neurosurgery
  • Pediatric oncology
  • Neurosurgical oncology

Background:

  • Intracranial meningiomas are rare pediatric brain tumors, comprising 0.4-4.6% of primary tumors in individuals aged 0-18 years.
  • This study focuses on the specific characteristics and management of meningiomas in this young population.

Purpose of the Study:

  • To retrospectively analyze the epidemiological, clinical, radiological, and histopathological features of pediatric intracranial meningiomas.
  • To evaluate the management strategies and outcomes for children diagnosed with these tumors.

Main Methods:

  • Retrospective analysis of 18 consecutive pediatric meningioma cases (age 0-18 years) operated between 1974-2005.
  • Data collected included epidemiological profile, clinical presentation, radiological findings, surgical excision details, and histopathological diagnoses.

Main Results:

  • The average age at presentation was 12.81 years, with a male-to-female ratio of 1.57:1.
  • Increased incidence observed in patients with neurofibromatosis; common locations included intraventricular and skull base.
  • Total tumor excision was successfully achieved in all evaluated cases.

Conclusions:

  • Pediatric intracranial meningiomas exhibit a higher incidence of atypical and aggressive subtypes compared to adults.
  • Favorable prognosis is associated with complete tumor resection and benign histopathological findings in pediatric patients.
Keywords:
Meningiomachildhood meningiomaneurofibromatosispediatric neoplasms

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...