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Dandy-Walker variant associated with bipolar affective disorder
Anand Lingeswaran1, Deepak Barathi, Gyaneswahr Sharma
1Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, A Unit of Sri Balaji Vidyapeeth University, Pondy-Cuddalore Main Road, Pillayarkuppam, Pondicherry - 607 402, India.
Journal of Pediatric Neurosciences
|September 3, 2011
Summary
This case report describes a rare association between Dandy-Walker variant, a congenital brain malformation, and acute mania in a 10-year-old boy. The findings highlight a potential link between neurological conditions and psychiatric disorders.
Area of Science:
- Neuroscience
- Child Psychiatry
- Developmental Neurology
Background:
- Dandy-Walker malformation is a congenital brain anomaly affecting the cerebellum and fourth ventricle.
- The association between Dandy-Walker syndrome and bipolar disorder type I mania has not been previously documented.
Observation:
- A 10-year-old boy presented with acute manic symptoms.
- Brain MRI revealed a Dandy-Walker variant, characterized by a posterior fossa cystic lesion, enlarged cisterna magna, and cerebellar vermis hypoplasia without hydrocephalus.
Findings:
- The patient exhibited symptoms consistent with acute mania.
- Magnetic Resonance Imaging (MRI) confirmed a Dandy-Walker variant.
Implications:
- This case suggests a potential, previously undescribed association between Dandy-Walker variant and acute mania.
- Further research is warranted to explore the neurobiological underpinnings of this association.
- Early diagnosis and management of both neurological and psychiatric conditions are crucial for affected children.
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