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Malignancies metastatic to the pleura
R A Matthay1, L Coppage, C Shaw
1Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Investigative Radiology
|May 1, 1990
Summary
Neoplasms of the pleura are a common cause of pleural effusion in individuals over 50. This review covers the causes, diagnosis, and treatment of pleural neoplasms and effusions.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Neoplasms are a significant cause of pleural effusion in patients over 50.
- Malignant pleural disease is frequently caused by lung, breast, ovarian, and stomach cancers, with adenocarcinoma being the most common type.
Purpose of the Study:
- To provide a comprehensive review of pleural neoplasms.
- To discuss the etiology, pathogenesis, clinical manifestations, diagnosis, prognosis, and treatment of malignant and paramalignant pleural effusions.
Main Methods:
- Literature review of neoplasms involving the pleura.
- Detailed discussion of malignant and paramalignant pleural effusions.
Main Results:
- Pleural neoplasms are the second most common cause of pleural effusion after congestive heart failure in patients over 50.
- Adenocarcinoma is the predominant cell type in malignant pleural disease.
Conclusions:
- Understanding the multifaceted aspects of pleural neoplasms is crucial for effective patient management.
- This review synthesizes current knowledge on pleural effusions secondary to cancer.