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In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
[Thromboembolic events and air travel]
Frédéric Lapostolle1, Claude Lapandry, Frédéric Adnet
1Hôpital Avicenne, Samu 93, 93009 Bobigny, France. frederic.lapostolle@avc.aphp.fr
Abstract:
Relation between air travel and thromboembolic events is clearly demonstrated. The risk increases for travel of more than 5,000 km. Women are suspected to have an increased risk. However, the role of other potential thromboembolic risk factors remains unknown. The role of hypoxia and hypobaria, of the class traveled and of usual thromboembolic risk factors are unclear. Then, prophylactic strategy has to be decided regarding risk related to both travel and patient. Compartmental prophylactic therapy is largely indicated. Elastic stocking is widely recommended. Pharmacologic prophylactic therapy should be rarely indicated and discussed case by case.
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