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Updated: May 29, 2026
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Measuring Global Cellular Matrix Metalloproteinase and Metabolic Activity in 3D Hydrogels
Published on: January 22, 2019
A graphene oxide-peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix
Duan Feng1, Yangyang Zhang, Tingting Feng
1Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Chemical Communications (Cambridge, England)
|September 6, 2011
Abstract:
A graphene oxide-peptide based fluorescence sensor has been developed for matrix metalloproteinase 2 (MMP2), and its applicability has been demonstrated by monitoring the concentration of MMP2 secreted by HeLa cells, revealing that HeLa cells with a density of 5.48 × 10(5) cells per mL can produce 22 nM in cell culture media in 24 h.
