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Three new megastigmanes from the leaves of Annona muricata
Ayano Matsushige1, Katsuyoshi Matsunami, Yaichiro Kotake
1Department of Xenobiotic Metabolism and Molecular Toxicology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Abstract:
Three new megastigmanes (1-3), named annoionols A and B (1, 2) and annoionoside (3), were isolated from the leaves of Annona muricata L. (Annonaceae) together with 14 known compounds (4-17). Among the known compounds, annoionol C (4) was isolated from a natural source for the first time. The structures of all compounds were elucidated by spectroscopic and chemical analyses.
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