Cutaneous carcinogenesis: a review of recent advances in pathogenesis

The clinical spectrum of cutaneous carcinogenesis has not changed substantially. New insights into the pathogenesis of ultraviolet induced lesions have resulted in better understanding of the basic biology of cutaneous tumours. This has evolved into the development of 4 stages in skin carcinogenesis. New problems like Human Immunodeficiency Virus (HIV), associated tumours and ozone depletion are emerging, which will require greater research efforts into preventing a further increase in incidence.