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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Related Experiment Video

Updated: May 29, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

Methadone and lung transplants.

Aurélie Maricq1, Denis Jacques, Nicolas Zdanowicz

  • 1Université Catholique de Louvain, 5530 Yvoir, Belgium.

Psychiatria Danubina
|September 7, 2011
PubMed
Summary

Liaison psychiatrists play a crucial role in pulmonary pre-transplantation assessments for patients on methadone, despite a lack of specific guidelines. Managing methadone treatment requires careful consideration of its psycho-social impacts on post-operative prognosis.

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Area of Science:

  • Psychiatry
  • Pulmonology
  • Transplantation Medicine

Background:

  • Pulmonary transplantation requires thorough pre-operative assessment of patient habits and potential risks.
  • Methadone treatment presents unique challenges in pre-transplant evaluations due to its psycho-social and physiological effects.
  • Current guidelines for managing methadone in pulmonary transplant candidates are lacking.

Purpose of the Study:

  • To elucidate the role of liaison psychiatry in pulmonary pre-transplantation assessment for patients undergoing methadone therapy.
  • To understand the influence of methadone on post-operative prognosis within a bio-psycho-social framework.

Main Methods:

  • Data collection on patient habits prior to pulmonary transplantation.
  • Literature review on methadone's effects, side-effects, and potential guidelines.
  • Application of the bio-psycho-social model to assess methadone's impact on prognosis.

Main Results:

  • Methadone-treated patients constitute a small percentage (4.3%) but represent a significant stressor for psychiatric and multidisciplinary teams.
  • Methadone's pulmonary, cardiac, urologic, drug, and immune side effects are identifiable and manageable.
  • A comprehensive assessment considering patient history, addiction, physical condition, and treatment is vital for estimating prognosis.

Conclusions:

  • No definitive guidelines exist for methadone treatment duration in pulmonary transplant candidates.
  • Methadone offers patient stabilization and relapse minimization, weighed against risks like confusion, pain management difficulties, and immune suppression.
  • Psychoeducation, patient support, and shared decision-making are recommended for managing these patients.