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Related Concept Videos

Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
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Related Experiment Video

Updated: May 29, 2026

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
08:50

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy

Published on: June 25, 2013

Pre-induction low dose pethidine does not decrease incidence of postoperative shivering in laparoscopic gynecological

Ishwar Bhukal1, Sohan Lal Solanki, Sushil Kumar

  • 1Department of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Anaesthesiology, Clinical Pharmacology
|September 8, 2011
PubMed
Summary
This summary is machine-generated.

Pre-induction, low-dose pethidine did not significantly prevent postoperative shivering in gynecological laparoscopic surgeries. Shivering incidence and severity were similar across groups, indicating limited prophylactic benefit.

Keywords:
Laparoscopypethidinepostoperative shivering

Related Experiment Videos

Last Updated: May 29, 2026

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
08:50

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy

Published on: June 25, 2013

Area of Science:

  • Anesthesiology
  • Gynecological Surgery
  • Postoperative Care

Background:

  • Postoperative shivering occurs in approximately 40% of patients undergoing laparoscopic procedures.
  • Shivering can delay hospital discharge and cause patient discomfort.
  • Laparoscopic gynecological surgeries are frequently performed on an outpatient basis.

Purpose of the Study:

  • To evaluate the efficacy of prophylactic, low-dose pethidine administered before induction of anesthesia in preventing postoperative shivering.
  • To assess the impact of different pethidine dosages (0.3 mg/kg and 0.5 mg/kg) on shivering incidence and severity.

Main Methods:

  • A randomized study involving 60 female patients (ASA class 1-2, age 25-35) undergoing laparoscopic gynecological surgery.
  • Patients were divided into three groups: two receiving different doses of intravenous pethidine, and one receiving intravenous normal saline before anesthesia induction.
  • Core body temperature and shivering severity were monitored throughout the perioperative period.

Main Results:

  • No statistically significant difference in the incidence or grading of postoperative shivering was observed between the pethidine groups and the saline group (P > 0.05).
  • Core body temperatures were comparable across all groups before induction, after induction, and in the post-anesthesia care unit (PACU).
  • Shiverers exhibited significantly lower core body temperatures in the PACU compared to non-shiverers.

Conclusions:

  • Prophylactic administration of low-dose pethidine prior to anesthesia induction does not significantly reduce postoperative shivering in patients undergoing laparoscopic gynecological surgery.
  • The findings suggest that low-dose pethidine has a limited role in preventing this common postoperative complication.