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Related Experiment Video

Updated: May 29, 2026

Making Precise and Accurate Single-Molecule FRET Measurements using the Open-Source smfBox
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Published on: July 5, 2021

Sepbox technique in natural products.

M Bhandari1, Anil Bhandari, A Bhandari

  • 1Department of Pharmacognosy, Jodhpur College of Pharmacy, Jodhpur National University, Jodhpur, India.

Journal of Young Pharmacists : JYP
|September 8, 2011
PubMed
Summary

Natural compound separation is challenging and expensive. The automated sepbox technology significantly speeds up sample preparation, offering economic benefits for research and development.

Keywords:
High-throughput screeningnatural compoundsseparationsepbox

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Area of Science:

  • Natural product chemistry
  • Analytical chemistry
  • Process automation

Background:

  • Natural compounds are crucial in research and development, offering structural diversity.
  • High-throughput screening (HTS) has accelerated compound testing, but sample preparation remains a bottleneck.
  • Current methods for fractionating and separating natural compounds are time-consuming, tedious, and costly.

Purpose of the Study:

  • To address the limitations of conventional sample preparation methods for natural products.
  • To introduce and evaluate the efficiency of the sepbox technology for automated sample processing.
  • To highlight the economic potential of automating natural compound separation.

Main Methods:

  • Utilizing the sepbox system for automated fractionation and separation of natural samples.
  • Comparing the processing speed of the sepbox technology against conventional methods.
  • Assessing the overall efficiency and economic viability of automated sample preparation.

Main Results:

  • The sepbox technology enables automated processing of samples from natural resources.
  • Sepbox processing is up to 30 times faster than conventional separation methods.
  • Automation of sample preparation presents significant economic advantages.

Conclusions:

  • The sepbox concept offers a substantial improvement in the speed and efficiency of natural compound separation.
  • Automated sample preparation using sepbox technology has considerable economic potential for research and development.
  • This technology can overcome the challenges associated with traditional, labor-intensive natural product isolation.