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Doxycycline induced generalized bullous fixed drug eruption - A case report
Selvaraj Nitya1, Kameswari Deepa1, Adhimoolam Mangaiarkkarasi1
1Department of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry 605107, India.
Journal of Young Pharmacists : JYP
|February 25, 2014
Summary
Adverse drug reactions pose significant risks in medicine. This case study details a bullous fixed drug eruption caused by doxycycline, a common antibiotic, in a 37-year-old female patient.
Area of Science:
- Dermatology
- Pharmacovigilance
- Internal Medicine
Background:
- Adverse drug reactions (ADRs) are a significant concern in healthcare.
- Fixed drug eruption (FDE) is a specific type of cutaneous ADR.
- FDE commonly occurs with antimicrobials and analgesics.
Purpose of the Study:
- To report a case of bullous fixed drug eruption.
- To highlight doxycycline as a potential causative agent for FDE.
- To contribute to the understanding of FDE presentation and triggers.
Main Methods:
- Case report of a 37-year-old female patient.
- Clinical presentation and diagnosis of bullous fixed drug eruption.
- Identification of doxycycline as the suspected drug.
Main Results:
- The patient presented with bullous lesions consistent with FDE.
- Doxycycline administration was identified as the trigger for the eruption.
- The reaction was characterized as a bullous form of FDE.
Conclusions:
- Doxycycline can induce bullous fixed drug eruptions.
- Early recognition and drug withdrawal are crucial for managing FDE.
- This case underscores the importance of considering FDE in patients presenting with characteristic skin lesions after drug exposure.
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