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Diet and metabolic development.

M T Little1, P Hahn

  • 1Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|June 1, 1990
PubMed
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Dietary changes during development significantly impact cholesterol and fatty acid metabolism, with lasting effects observed across prenatal, suckling, and weaning stages in animal studies.

Area of Science:

  • Developmental biology
  • Nutritional science
  • Metabolic regulation

Background:

  • Environmental factors influence genetically regulated development.
  • Dietary manipulation can induce metabolic processes.
  • Animal studies show persistent effects of developmental nutrition.

Purpose of the Study:

  • Review the impact of diet on metabolic development.
  • Examine persistent effects of nutritional factors.
  • Focus on cholesterol and fatty acid metabolism.

Main Methods:

  • Review of animal studies on dietary manipulation.
  • Analysis of metabolic changes during development.
  • Identification of critical developmental periods.

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Main Results:

  • Dietary factors induce metabolic processes during development.
  • Persistent and permanent effects on cholesterol and fatty acid metabolism observed.
  • Critical developmental windows (prenatal, suckling, weaning) identified for dietary influence.

Conclusions:

  • Nutritional factors exert significant control over metabolic development.
  • Dietary interventions during specific developmental phases have lasting consequences.
  • Understanding these mechanisms is crucial for developmental health.