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Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.

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Related Experiment Video

Updated: May 29, 2026

A Customizable Chamber for Measuring Cell Migration
07:33

A Customizable Chamber for Measuring Cell Migration

Published on: March 12, 2017

Analysis of cellular migration using a two-chamber methodology.

Michelle M Kouspou1, John T Price

  • 1Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, VIC, Australia.

Methods in Molecular Biology (Clifton, N.J.)
|September 8, 2011
PubMed
Summary
This summary is machine-generated.

Directed cell migration is crucial for development and disease. This study introduces a reusable, inexpensive multiwell microchemotaxis assay for studying cell movement and heat shock protein involvement.

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Related Experiment Videos

Last Updated: May 29, 2026

A Customizable Chamber for Measuring Cell Migration
07:33

A Customizable Chamber for Measuring Cell Migration

Published on: March 12, 2017

Study of Cell Migration in Microfabricated Channels
09:36

Study of Cell Migration in Microfabricated Channels

Published on: February 21, 2014

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay
11:20

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay

Published on: November 17, 2017

Area of Science:

  • Cell Biology
  • Biochemistry
  • Physiology

Background:

  • Directed cell migration is essential for embryogenesis, wound healing, and cancer metastasis.
  • Heat shock proteins (HSPs) and transcription factors play significant roles in cell migration.
  • Traditional two-chamber assays exist but have limitations.

Purpose of the Study:

  • To introduce and validate a novel multiwell microchemotaxis migration assay.
  • To highlight the assay's advantages over existing methods for studying cell migration.

Main Methods:

  • Utilized a multiwell microchemotaxis assay for cell migration studies.
  • Focused on assessing the role of heat shock proteins in cell migration.

Main Results:

  • The described assay is reusable, inexpensive, and highly reproducible.
  • It requires only a small volume of reagents, making it efficient.

Conclusions:

  • The multiwell microchemotaxis assay is a practical and effective tool for studying directed cell migration.
  • This method facilitates research into the involvement of heat shock proteins in physiological and pathophysiological processes.