Related Experiment Video
Updated: May 29, 2026

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
Published on: June 8, 2019
[Trophoblastic diseases: a multidisciplinary approach, a first Swiss center]
A-L Rougemont1, M-F Pelte, F Sloan Béna
1Service de pathologie clinique, Département de médecine génétique et de laboratoire, HUG, Genève. Anne-Laure.Rougemont@hcuge.ch
Abstract:
Trophoblastic diseases are rare and complex. The Center for trophoblastic diseases, the first in Switzerland, was founded in Geneva in January 2009 to formalize the collaboration between obstetricians-gynecologists, pathologists, geneticists, radiologists and oncologists. At the physician's request and with patient consent, an integrative diagnosis is proposed after centralized review of the histological slides, anti-p57KIP2 immunohistochemistry, and ploidy analysis by QF-PCR (Quantitative fluorescent polymerase chain reaction). The referring physician receives treatment and beta-hCG dosage recommendations. This pluridisciplinary diagnostic and therapeutic approach allows optimal surveillance and treatment of patients.
