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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
Published on: September 28, 2022
Design and facile solid-phase synthesis of conformationally constrained bicyclic peptoids
Ji Hoon Lee1, Han-Sung Kim, Hyun-Suk Lim
1Department of Biochemistry and Molecular Biology, and Indiana University Simon Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Organic Letters
|September 10, 2011
Abstract:
Triazine-bridged bicyclic peptoids as conformationally constrained peptidomimetics are described. Bicyclic peptoids composed of 6-12 peptoid residues (m, n = 3-6) were synthesized in excellent yields using a highly efficient solid-phase synthetic route.
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