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Updated: May 29, 2026
14:38
Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Three cases using platelet-rich plasma to cure chronic soft tissue lesions
Ji Liu1, Ting Yuan, Changqing Zhang
1Department of Orthopedics, Sixth People's Hospital Affiliated Shanghai JiaoTong University, Shanghai 200233, PR China.
Summary
Platelet-rich plasma (PRP) therapy offers a novel solution for chronic non-healing wounds. This study shows successful wound healing and no recurrence in three patients treated with PRP.
Area of Science:
- Regenerative Medicine
- Wound Healing Research
- Biologics in Medicine
Background:
- Chronic non-healing wounds pose a significant clinical challenge.
- Conventional treatments, including debridement and growth factors, may be insufficient for some patients.
- Platelet-rich plasma (PRP) is an autologous blood derivative with potential therapeutic benefits.
Observation:
- Three cases of patients with chronic non-healing wounds were treated with PRP therapy.
- PRP was prepared from autologous whole blood and applied topically to the wounds after debridement.
- Wound re-evaluation and further treatment were performed at 7-10 day intervals.
Findings:
- All three patients experienced complete wound healing.
- No recurrence of wounds was reported post-treatment.
- Visual documentation of the treatment process and outcomes was provided.
Implications:
- PRP therapy presents a promising alternative for managing chronic wounds unresponsive to standard care.
- This approach may serve as a substitute for conventional treatments when efficacy is limited.
- Further research into PRP's role in wound healing is warranted.
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