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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...

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Related Experiment Video

Updated: May 29, 2026

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury
07:02

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

Published on: February 10, 2026

[Chronic kidney insufficiency in children].

Emma Allain-Launay1, Gwénaëlle Roussey-Kesler

  • 1CHU de Nantes, hôpital Mère-Enfants, clinique médicale pédiatrique, néphrologie pédiatrique, 44093 Nantes cedex, France. emma.allainlaunay@chu-nantes.fr

Presse Medicale (Paris, France : 1983)
|September 13, 2011
PubMed
Summary

Chronic kidney insufficiency in children often stems from congenital or inherited conditions, impacting growth and nutrition. Management focuses on dialysis or transplantation, with specific pediatric considerations for each treatment.

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Last Updated: May 29, 2026

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Area of Science:

  • Pediatric Nephrology
  • Renal Medicine
  • Child Health

Context:

  • Chronic kidney insufficiency (CKI) in children presents with failure to thrive, feeding disorders, or excessive thirst.
  • Congenital or inherited conditions account for over 50% of pediatric CKI cases.
  • Key challenges include managing growth, nutrition, and renal osteodystrophy.

Purpose:

  • To outline the key considerations in diagnosing and managing chronic kidney insufficiency in pediatric patients.
  • To highlight the primary therapeutic modalities and their associated challenges in children.

Summary:

  • CKI diagnosis in children should consider symptoms like failure to thrive and excessive thirst.
  • Congenital/inherited diseases are the leading causes, necessitating focus on growth, nutrition, and bone health.
  • Peritoneal dialysis is preferred for younger children, while kidney transplantation offers the best outcome for end-stage renal failure in children over 10 kg.

Impact:

  • Informs pediatricians and nephrologists on CKI recognition and management strategies.
  • Emphasizes the importance of multidisciplinary care, including psychological and social support.
  • Underscores specific risks in pediatric kidney transplantation, such as thrombosis and post-transplant lymphoproliferative disorders.