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[Chronic kidney insufficiency in children]

Emma Allain-Launay1, Gwénaëlle Roussey-Kesler

  • 1CHU de Nantes, hôpital Mère-Enfants, clinique médicale pédiatrique, néphrologie pédiatrique, 44093 Nantes cedex, France. emma.allainlaunay@chu-nantes.fr

Presse Medicale (Paris, France : 1983)
|September 13, 2011
PubMed

Insights

Chronic kidney insufficiency in children often stems from congenital or inherited conditions, impacting growth and nutrition. Management focuses on dialysis or transplantation, with specific pediatric considerations for each treatment.

Area of Science:

  • Pediatric Nephrology
  • Renal Medicine
  • Child Health

Context:

  • Chronic kidney insufficiency (CKI) in children presents with failure to thrive, feeding disorders, or excessive thirst.
  • Congenital or inherited conditions account for over 50% of pediatric CKI cases.
  • Key challenges include managing growth, nutrition, and renal osteodystrophy.

Purpose:

  • To outline the key considerations in diagnosing and managing chronic kidney insufficiency in pediatric patients.
  • To highlight the primary therapeutic modalities and their associated challenges in children.

Summary:

  • CKI diagnosis in children should consider symptoms like failure to thrive and excessive thirst.
  • Congenital/inherited diseases are the leading causes, necessitating focus on growth, nutrition, and bone health.
  • Peritoneal dialysis is preferred for younger children, while kidney transplantation offers the best outcome for end-stage renal failure in children over 10 kg.

Impact:

  • Informs pediatricians and nephrologists on CKI recognition and management strategies.
  • Emphasizes the importance of multidisciplinary care, including psychological and social support.
  • Underscores specific risks in pediatric kidney transplantation, such as thrombosis and post-transplant lymphoproliferative disorders.

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