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The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Chondrosarcoma in a dromedary camel (Camelus dromedarius)
Kyathanahalli S Janardhan1, Chanran K Ganta, Gordon A Andrews
1Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA. kjanardh@vet.k-state.edu
Summary
A dromedary camel developed carpal joint swelling and lameness due to chondrosarcoma. This bone cancer infiltrated the carpus and metacarpus, leading to pulmonary metastasis and euthanasia.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
- Camelid Medicine
Background:
- Dromedary camels can develop various neoplastic conditions.
- Carpal joint disorders in camels often present with lameness and swelling.
Observation:
- A 4-year-old female dromedary camel exhibited progressive left carpal swelling and lameness for 7 months.
- Radiographs revealed multifocal lytic lesions in the carpal and proximal metacarpal bones.
- Necropsy identified a large soft tissue mass infiltrating the carpal and metacarpal bones, with pulmonary nodules.
Findings:
- Histopathology and immunohistochemistry confirmed chondrosarcoma originating from the carpal joint.
- Neoplastic cells stained positive for vimentin and S-100.
- The tumor infiltrated carpal and metacarpal bones and metastasized to the lungs.
Implications:
- This case highlights chondrosarcoma as a differential diagnosis for carpal masses and lameness in dromedary camels.
- Early detection and understanding of bone tumors in camelids are crucial for prognosis.
- Further research into camelid oncology can improve diagnostic and therapeutic strategies.

