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Updated: May 29, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea

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Published on: November 9, 2016

Botulinum toxin dosage template for frontal wrinkle effacement.

Ivo Sternick¹, Ivo Pitanguy

¹Ivo Pitanguy Institute of Plastic Surgery, Rio de Janiero, Brazil. ivosternick@uol.com.br

Aesthetic Surgery Journal

|September 13, 2011

Summary

A novel "dose disc" template aids precise botulinum toxin placement for natural-looking frontal wrinkle reduction. This method improves injection accuracy and minimizes side effects, offering a practical solution for aesthetic treatments.

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Published on: March 3, 2014

Area of Science:

Aesthetic Medicine
Dermatology
Cosmetic Procedures

Background:

Lack of consensus on optimal botulinum toxin injection techniques for natural frontal aesthetics.
Need for standardized methods to guide precise toxin placement.

Purpose of the Study:

Introduce a safe and effective "dose disc" template for botulinum toxin injections in the frontal region.
Achieve natural wrinkle effacement while preserving some facial movement.
Provide a practical method for estimating toxin spread and guiding injection positioning.

Main Methods:

Study included 50 adult patients with frontal expression wrinkles.
Patients were divided into two groups for sequential or simultaneous frontal and glabellar injections.
All injections utilized the "dose disc" for pretreatment marking and positioning.

Main Results:

317 injections were performed using the dose disc with a low failure rate (7/50 patients).
Failures were primarily due to irregular disc positioning, with successful correction via additional injections.
No significant side effects like palpebral or eyebrow ptosis were observed.

Conclusions:

The fixed "dose disc" template is a valuable tool for accurate botulinum toxin injections in the frontal area.
Further research is needed for optimized disc models, varied doses, and application to other facial regions.
The goal is to enhance treatment efficacy, duration, and expand template utility.