Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acne Infection

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2 (COX-2),...

Candidiasis

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adaptive laboratory evolution enables microbial access to untreated, virgin high-density polyethylene under environmentally relevant conditions.

Journal of hazardous materials·2026

Same author

A practical and validated nomogram for predicting delirium in critically ill patients: A multicenter prospective observational study.

Respiratory medicine·2026

Same author

Combined Clavicular Hook Plate and Coracoid Screw Fixation for Coracoid Process Fractures Associated with Acromioclavicular Joint Dislocation.

Medicina (Kaunas, Lithuania)·2026

Same author

Epidemiology of severe acute respiratory infections in South Korea: a nationwide surveillance study.

BMC pulmonary medicine·2025

Same author

A new biological enhancement therapy for anterior cruciate ligament reconstruction: the preclinical proof of anterior cruciate ligament reconstruction with tendon graft reseeded with autologous anterior cruciate ligament-derived cells.

Stem cell research & therapy·2025

Same author

Cerebrolysin treatment in a case of post-herpes simplex encephalitis with neuropsychiatric symptoms.

Journal of medicine and life·2025

Search research articles

Related Experiment Videos

Blastomycosis-like Pyoderma with Good Response to Acitretin.

Young Seok Lee¹, Se Won Jung, Hyun Soo Sim

¹Department of Dermatology, Maryknoll Medical Center, Busan, Korea.

Annals of Dermatology

|September 13, 2011

Summary

Blastomycosis-like pyoderma, a rare skin condition, showed significant improvement with acitretin treatment in a patient with Down syndrome. This suggests acitretin as a potential therapy for this challenging condition.

Keywords:

Acitretin Blastomycosis-like pyoderma

Related Experiment Videos

Area of Science:

Dermatology
Infectious Diseases
Genetics

Background:

Blastomycosis-like pyoderma is a rare, vegetating skin lesion.
It represents an exaggerated tissue reaction to bacterial infection.
Predisposing factors can include conditions like Down syndrome, diabetes mellitus, and hypothyroidism.

Observation:

A case report details a patient with Down syndrome, diabetes mellitus, and hypothyroidism.
This patient presented with blastomycosis-like pyoderma.
Conventional therapies, including antibiotics, were ineffective over a prolonged period.

Findings:

The patient experienced dramatic improvement after 3 months of acitretin treatment.
Acitretin demonstrated efficacy where other treatments failed.
This highlights a potential therapeutic role for retinoids.

Implications:

Acitretin may be a valuable treatment option for refractory blastomycosis-like pyoderma.
Further research into retinoid therapy for this condition is warranted.
Understanding treatment responses in patients with comorbidities like Down syndrome is crucial.