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Clinical experience with polymethylmethacrylate microsphere filler complications
Tae Hwan Park1, Sang Won Seo, June-Kyu Kim
1Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul, 110-746, Korea. hard-piano@hanmail.net
Aesthetic Plastic Surgery
|September 13, 2011
Summary
Polymethylmethacrylate (PMMA) filler injections can cause complications like nodules and inflammation. Early and delayed adverse reactions require varied treatments due to the lack of standard protocols.
Area of Science:
- Dermatology
- Plastic Surgery
- Cosmetic Procedures
Background:
- Polymethylmethacrylate (PMMA) is a common filler for wrinkle correction, valued for lasting results and low complication rates.
- Despite its benefits, PMMA filler injections can lead to various early and delayed complications.
- This study reviews complications encountered at a single institution over a five-year period.
Observation:
- Thirteen cases of PMMA filler complications were evaluated and treated.
- The patient demographic was predominantly female (92.3%).
- Common complications included nodular masses, inflammation, allergic reactions, and discoloration affecting facial areas like lips and cheeks.
Findings:
- Complications presented as nodular masses, inflammation, allergic reactions, and discoloration.
- Affected sites included lips, periocular areas, nasolabial folds, forehead, marionette lines, and cheeks.
- Treatment varied due to the absence of standardized protocols, with intralesional steroids and surgical excision used for lip granulomas.
Implications:
- The findings highlight the need for further research into PMMA injection safety and risk factors.
- Developing standardized treatment protocols for PMMA filler complications is crucial.
- Minimizing morbidity associated with PMMA filler adverse events requires ongoing investigation and improved management strategies.