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Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Role of ventriculoperitoneal shunt surgery in grade IV tubercular meningitis with hydrocephalus
Jing Peng1, Xiaolu Deng, Fang He
1Department of Pediatrics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha, Hunan, People's Republic of China.
Insights
Ventriculoperitoneal shunt (VPS) placement in children with severe tuberculous meningitis and hydrocephalus (TBMH) shows clinical value. Direct VPS surgery may improve outcomes, with external ventricular drainage response not being a reliable predictor for shunt benefit.
Area of Science:
- Pediatric Neurosurgery
- Infectious Diseases
- Neurology
Background:
- Hydrocephalus is a frequent complication of tuberculous meningitis (TBM) in children.
- The efficacy of ventriculoperitoneal shunt (VPS) placement in advanced (grade IV) TBM with hydrocephalus (TBMH) remains debated.
Purpose of the Study:
- To evaluate the clinical utility of VPS placement for pediatric patients diagnosed with grade IV TBMH.
- To assess the outcomes associated with VPS in this specific patient cohort.
Main Methods:
- A cohort of 19 children with grade IV TBMH underwent VPS placement combined with medical treatment.
- External ventricular drainage (EVD) was reserved for cases with severe metabolic disturbances or brainstem dysfunction requiring pre-surgical correction.
- Patient outcomes were categorized as normal, mild sequelae, severe sequelae, death, or vegetative state.
Main Results:
- Over a mean follow-up of 29 months, 3 patients died, 4 fully recovered, 8 had mild sequelae, and 4 experienced severe sequelae.
- Six shunt-related complications were documented among the study participants.
- The overall outcome suggests potential benefits from VPS intervention.
Conclusions:
- Direct ventriculoperitoneal shunt surgery appears to enhance outcomes for children with grade IV TBMH.
- Reliance on the response to external ventricular drainage is not a dependable method for identifying patients who would benefit from subsequent shunt surgery.
Purpose:
Hydrocephalus is a common complication of tuberculous meningitis (TBM) in children. The role of ventriculoperitoneal shunt (VPS) placement in grade IV patients is controversial. The aim of this study is to investigate the clinical value of VPS placement for patients with grade IV TBM with hydrocephalus (TBMH).
Methods:
This study was carried out on children with grade IV TBMH from January 2006 to January 2011 in Xiangya Hospital, China. All patients were given VPS placement combined with medicine treatment. External ventricular drainage (EVD) was performed only in the presence of severe biochemical derangements or brainstem dysfunction requiring correction before shunt surgery. Outcomes were divided into normal, mild sequelae, severe sequelae, death, or vegetable status.
Results:
A total of 19 children with grade IV TBMH were recruited into the study. The average follow-up period was 29 months. Three of the 19 patients expired, four patients had a full recovery, eight had slight sequelae, and four had severe sequelae. Six complications related to the shunt surgery were seen among the patients.
Conclusions:
This study demonstrates that direct ventriculoperitoneal shunt surgery could improve the outcome of grade IV TBMH. The response to EVD is not a reliable indication for selecting patients who would benefit from shunt surgery.
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