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Updated: May 29, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Endourologic procedures for benign prostatic hyperplasia: review of indications and outcomes
Ravi Kacker1, Stephen B Williams
1Department of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 20015, USA.
Purpose:
To discern the positive and negative attributes of the various treatment modalities for benign prostatic hyperplasia.
Materials And Methods:
A comprehensive literature review is presented for endoscopic treatment of the bladder outlet obstruction with an emphasis on current randomized controlled trials available comparing these treatment modalities.
Results:
Transurethral resection of the prostate remains the gold standard when assessing alternative treatment options available for benign prostatic hyperplasia. Holmium laser enucleation of the prostate demonstrates equivalent efficacy with a more favorable risk profile. Photoselective vaporization, transurethral needle ablation, and transurethral microwave therapy have demonstrated safety and short-term efficacy; however, data on long-term efficacy are currently lacking.
Conclusion:
The current endoscopic methods may offer favorable safety and efficacy for the treatment of the bladder outlet obstruction. However, further research is needed to establish long-term efficacy for many of the currently available treatment options.
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