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Updated: May 29, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Factors associated with parental perception of child vulnerability 12 months after abnormal newborn screening results

Audrey Tluczek1, Anne Chevalier McKechnie, Roger L Brown

  • 1School of Nursing, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53792, USA.

Research in Nursing & Health
|September 13, 2011
PubMed

Insights

Parental perceptions of child vulnerability are linked to female sex, cystic fibrosis (CF) diagnosis, and frequent illness. Infants with CF or CF carrier status experienced more illnesses, highlighting a need for further research into CF carrier infants.

Area of Science:

  • Pediatric Health
  • Genetics
  • Psychology

Background:

  • Newborn screening (NBS) identifies infants with serious genetic conditions.
  • Parental perceptions of child vulnerability (PPCV) can impact child well-being.
  • Understanding factors influencing PPCV post-NBS is crucial for targeted support.

Purpose of the Study:

  • To identify factors associated with elevated PPCV 12 months after NBS.
  • To explore the relationship between specific NBS results and PPCV.
  • To investigate the influence of infant illness frequency on PPCV.

Main Methods:

  • Mixed logit structural equation modeling was used.
  • Data collected from 136 children: healthy (H), cystic fibrosis carriers (CF-C), congenital hypothyroidism (CH), and cystic fibrosis (CF).
  • Controlled for infant and parent characteristics.

Main Results:

  • Elevated PPCV was directly associated with parent female sex, CF diagnosis, and high documented illness frequency.
  • PPCV positively correlated with maternal parenting stress.
  • Infants with CF and CF carriers had significantly more documented illness frequency than the H group.

Conclusions:

  • Parental factors and infant diagnosis (CF) significantly influence PPCV.
  • High illness frequency in CF carrier infants warrants further investigation.
  • Congenital hypothyroidism diagnosis did not significantly impact PPCV compared to healthy controls.

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