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Related Experiment Video

Updated: May 29, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Central corneal thickness in children.

1, Yasmin S Bradfield, B Michele Melia

  • 1Jaeb Center for Health Research, Tampa, FL 33647, USA. pedig@jaeb.org

Archives of Ophthalmology (Chicago, Ill. : 1960)
|September 14, 2011
PubMed
Summary

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Central corneal thickness (CCT) increases with age in children up to 11 years. African American children have thinner corneas than white and Hispanic children.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Corneal Physiology

Background:

  • Central corneal thickness (CCT) is a critical ocular biometric parameter.
  • Understanding CCT variations in pediatric populations is essential for accurate ophthalmic assessments.

Purpose of the Study:

  • To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years.
  • To investigate the influence of age, race, and ethnicity on CCT in children.

Main Methods:

  • Prospective observational multicenter study.
  • Central corneal thickness (CCT) measured using a handheld contact pachymeter.
  • Inclusion of 2079 children aged 0-17 years, including white, African American, and Hispanic participants.

Related Experiment Videos

Last Updated: May 29, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Main Results:

  • African American children exhibited thinner corneas (approx. 20 microm) compared to white and Hispanic children (P < .001).
  • Median CCT increased with age from 1 to 11 years, plateauing after age 11.
  • Higher intraocular pressure (IOP) correlated with thicker CCT (1.5 mm Hg per 100 microm), and myopia correlated with thinner CCT (1 microm per diopter).

Conclusions:

  • Median CCT shows age-dependent increases in children aged 1-11 years, most pronounced in younger age groups.
  • African American children have thinner central corneas on average than white and Hispanic children.
  • White and Hispanic children demonstrate similar CCT values.