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Lacrimo-auriculo-dento-digital syndrome.
Namrata R Mathrawala1, Rahul J Hegde
1Department of Pedodontics and Preventive Dentistry, Bharati Vidyapeeth University Dental College and Hospital, Navi Mumbai, India.
Journal of the Indian Society of Pedodontics and Preventive Dentistry
|September 14, 2011
Summary
Lacrimo-auriculo-dento-digital (LADD) syndrome is a rare genetic disorder affecting tear ducts, salivary glands, ears, teeth, and limbs. This case highlights the syndrome
Area of Science:
- Genetics
- Rare Diseases
- Craniofacial Anomalies
Background:
- Lacrimo-auriculo-dento-digital (LADD) syndrome is an autosomal dominant disorder.
- Characterized by abnormalities in the lacrimal/salivary systems, ears, teeth, and limbs.
- Often presents with dry mouth and enamel hypoplasia, leading to significant dental issues.
Observation:
- Presents a specific case of LADD syndrome.
- Details the clinical spectrum observed in the patient.
- Documents the therapeutic challenges encountered.
Findings:
- The case illustrates the complex presentation of LADD syndrome.
- Highlights the variability in the inheritance pattern and expressivity.
- Underscores the dental consequences, including enamel hypoplasia and dry mouth.
Implications:
- Emphasizes the need for early diagnosis and multidisciplinary management of LADD syndrome.
- Informs clinical practice regarding the dental and systemic manifestations.
- Contributes to understanding the genetic basis and clinical variability of LADD syndrome.
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