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Related Experiment Videos

Radiosurgery for acoustic neurinomas: early experience.

M E Linskey1, L D Lunsford, J C Flickinger

  • 1Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.

Neurosurgery
|May 1, 1990
PubMed
Summary

Stereotactic radiosurgery effectively controlled tumor growth in acoustic neurinoma patients. This gamma knife treatment demonstrated a promising role for managing selected acoustic neuromas with acceptable complication rates.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology

Background:

  • Acoustic neurinomas, also known as vestibular schwannomas, are benign tumors arising from the vestibulocochlear nerve.
  • Stereotactic radiosurgery (SRS) has emerged as a minimally invasive treatment option for these tumors.

Purpose of the Study:

  • To evaluate the early outcomes of stereotactic radiosurgery using a cobalt-60 gamma knife for acoustic neurinomas.
  • To assess tumor control, hearing preservation, and neurological complications in a cohort of patients.

Main Methods:

  • The study reviewed 26 patients with acoustic neurinomas treated with SRS.
  • Follow-up included serial imaging and audiological and neurological assessments over 6 to 19 months.

Main Results:

  • Tumor growth was arrested or reduced in all 26 patients.

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  • Hearing preservation was achieved in some patients, though some experienced hearing loss.
  • Delayed facial and trigeminal nerve deficits occurred but showed improvement.
  • No lower cranial nerve dysfunction was observed.

    • Conclusions:

    • Stereotactic radiosurgery is a viable alternative treatment for selected acoustic neurinoma patients.
    • The technique offers tumor control with an acceptable complication profile.
    • Longer follow-up is needed, but SRS shows potential for expanded use in acoustic neuroma management.